慢性阻塞性肺疾病的临床治疗进展
【摘要】 慢性阻塞性肺疾病(COPD)是呼吸内科临床上最为常见的慢性病之一,指的是一种以气流受限为主要临床表现的伴随有肺功能降低的呼吸道疾病,多见于中老年患者,预后较差,是目前导致患者死亡的主要疾病。目前临床对于COPD的治疗方案主要包括药物治疗、手术治疗、机械通气治疗、中药治疗、白蛋白治疗以及辅助锻炼治疗等,其主要目的在于改善患者的临床症状,控制病情进展。笔者就近年来中国知(CNKI)所收录的COPD治疗相关文献进行了检索和总结,对此类疾病的临床治疗进展进行了综述。
中国论文
【关键词】 慢性阻塞性肺疾病; 治疗进展; 药物治疗; 非药物治疗
【Abstract】 Chronic obstructive pulmonary disease (COPD) is one of the common chronic disease of respiratory department of internal medicine clinical most, refers to a airflow limitation as the main clinical manifestations of respiratory tract diseases associated with reduced lung function, more common in elderly patients, the prognosis is poor, is currently the leading cause of death in patients. Current clinical treatment for COPD mainly include drug treatment, operation treatment, mechanical ventilation in the treatment of traditional Chinese medicine, treatment, albumin therapy and assisted exercise therapy, and its main purpose is to improve the patient’s clinical symptoms, control the progress of the disease. The author in recent years China National Knowledge Infrastructure (CNKI) included in COPD treatment of related literatures were retrieved and summarized advances in the clinical treatment of these diseases are summarized.
【Key words】 Chronic obstructive pulmonary disease; Treatment progress; Drug therapy; Non drug therapy
First-author’s address:The People’s Hospital of Meizhou,Meizhou 514000,China
doi:10.3969/sn.1674-4985.2015.09.049
慢性阻塞性肺疾病(COPD)是呼吸内科临床上最为常见的慢性病之一,指的是一种以气流受限为主要临床表现的伴随有肺功能降低的呼吸道疾病,多见于中老年患者,预后较差,是目前导致患者死亡的主要疾病。虽然有相关指南说明此类疾病属于可预防、可治疗疾病,但目前临床实际治疗情况不容乐观,更侧重于患者的临床症状改善。笔者就COPD的主要临床治疗方案进行了总结,综述如下。
1 药物治疗
1.1 沙丁胺醇 沙丁胺醇在COPD急性期的治疗上应用十分广泛,该药物属于β2受体激动剂的一种,能够有效的保护肺组织,改善肺功能,通畅呼吸道。文献[1]研究显示,沙丁胺醇辅助治疗COPD急性发作期患者能够有效的改善患者的肺功能,与常规治疗方案的对照组相比有显著性差异(P0.05),但呼吸困难症状显著减轻,较对照组有显著差异(P