喜讯
《BMCComplementaryandAlternativeMedicine》:影响因子2.
“冠心舒通胶囊治疗慢性稳定型心绞痛(心血瘀阻证)多中心、随机、双盲、安慰剂平行对照临床试验”医院、中华医学会心血管病分会主任委员韩雅玲院士牵头,国内12医院共同参与研究。
Abstract
Background:ToassesstheefficacyandsafetyoforalGuanxinshutong(GXST)capsulesinChinesepatientswithstableanginapectoris(SAP)inaprospective,multicenter,double-Blind,placebo-controlled,randomizedclinicaltrial(clinicaltrials.govIdentifier:NCT).
Methods:Eligiblepatientswererandomized1:1totheGXSTorplacebogroup.Currentstandardantianginaltreatmentexceptfornitratedrugswascontinuedinbothgroups,whoreceivedanadditional4-weektreatmentofGXSTcapsuleorplacebo.Primaryendpointwasthechangefrombaselineinanginaattackfrequencyafterthe4-weektreatment.Secondaryendpointsincludedthereductionofnitroglycerindose,scoreofSeatntleAginaQuestionnaire,exercisetolerancetestdefinedastimetoonsetofchestpainandST-segmentdepressionatleast1mmgreaterthantherestingone.
Results:AtotalofSAPpatientsfrom12centersinChinawereenrolledbetweenJanuaryandOctober,andtheywererandomlydividedintotheGXSTgroupandtheplacebogroup(patientsineachgroup).Ofwhom,patients